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The capabilities of the VExUS ultrasound scale in predicting acute kidney injury in patients after cardiac surgery

https://doi.org/10.24835/1607-0771-435

Abstract

The aim: to evaluate the VExUS scale's ability to identify patients at high risk of developing acute kidney injury (AKI) after cardiac surgery.

Materials and Methods. The study included 69 patients who had undergone cardiac surgery. The average age of the patients was 59 years (range: 50 to 80 years). There were 48 (69.6%) men and 21 (30.4%) women. All patients underwent an ultrasound assessment of venous congestion using the VExUS protocol (assessment of the diameter of the inferior vena cava, Doppler examination of blood flow patterns in the hepatic, portal, and intrarenal veins). The study was conducted before surgery and in the early postoperative period. AKI was diagnosed according to the KDIGO criteria.

Results. AKI developed in 25 patients (36.2%) in the early postoperative period. When comparing groups of patients with and without AKI, statistically significant differences in the distribution of venous congestion grades according to the VExUS scale were detected only in the first 24 hours after surgery (p = 0.036). In a separate analysis, severe venous congestion (VExUS grade 3) was statistically significantly more common in patients with AKI (p = 0.013), whereas using a VExUS cutoff value of grade ≥2, no statistically significant association with the development of AKI was found.

Conclusion. severe venous congestion (VExUS grade 3) detected in the early postoperative period after cardiac surgery was statistically significantly more common in patients with AKI. Assessment of venous congestion using bedside ultrasound using the VExUS scale can be used as an additional method for identifying patients at high risk of developing AKI.

About the Authors

N. S. Klimentsova
Petrovsky Russian Research Center of Surgery
Russian Federation

Natalia S. Klimentsova – physician of the ultrasound diagnostics laboratory of the department of clinical physiology, instrumental and radiation diagnostics of Scientific and Clinical Center No. 1, Petrovsky Russian Research Center of Surgery, Moscow
https://orcid.org/0009-0000-3859-2206



Yu. R. Kamalov
Petrovsky Russian Research Center of Surgery
Russian Federation

Yuliy R. Kamalov – MD, PhD, Professor,

Head of the Ultrasound Diagnostics Laboratory, Department of Clinical Physiology, Instrumental and Radiation Diagnostics, Scientific and Clinical Center No. 1, Petrovsky Russian Research Center of Surgery, Moscow
https://orcid.org/0000-0002-6202-8506



E. N. Platova
Petrovsky Russian Research Center of Surgery
Russian Federation

Elena N. Platova – MD, PhD (Med.), Leading Researcher, Ultrasound Diagnostics Laboratory, Department of Clinical Physiology, Instrumental and Radiation Diagnostics, Scientific and Clinical Center No. 1, Petrovsky Russian Research Center of Surgery, Moscow
https://orcid.org/0000-0002-1059-3773



E. Yu. Kryzhanovskaya
Petrovsky Russian Research Center of Surgery
Russian Federation

Evgenia Yu. Kryzhanovskaya – MD, PhD (Med.), Leading Researcher, Ultrasound Diagnostics Laboratory, Department of Clinical Physiology, Instrumental and Radiation Diagnostics, Scientific and Clinical Center No. 1, Petrovsky Russian Research Center of Surgery, Moscow
https://orcid.org/0000-0001-9862-8266



References

1. Vandenberghe W., Gevaert S., Kellum J.A. et al. Acute Kidney Injury in Cardiorenal Syndrome Type 1 Patients: A Systematic Review and Meta-Analysis. Cardiorenal Med. 2016; 6 (2): 116–128. https://doi.org/10.1159/000442300

2. Hu J., Chen R., Liu S. et al. Global Incidence and Outcomes of Adult Patients With Acute Kidney Injury After Cardiac Surgery: A Systematic Review and Meta-Analysis. J. Cardiothorac. Vasc. Anesth. 2016; 30 (1): 82–89. https://doi.org/10.1053/j.jvca.2015.06.017

3. Oh S., Kwon S.H. Extracellular Vesicles in Acute Kidney Injury and Clinical Applications. Int. J. Mol. Sci. 2021; 22 (16): 8913. https://doi.org/10.3390/ijms22168913

4. Chen L., Hong L., Ma A. et al. Intraoperative venous congestion rather than hypotension is associated with acute adverse kidney events after cardiac surgery: a retrospective cohort study. Br. J. Anaesth. 2022; 128 (5): 785–795. https://doi.org/10.1016/j.bja.2022.01.032

5. Koratala A., Taleb Abdellah A., Reisinger N. Nephrologist-performed point-of-care venous excess Doppler ultrasound (VExUS) in the management of acute kidney injury. J. Ultrasound. 2023; 26 (1): 301–306. https://doi.org/10.1007/s40477-022-00760-6

6. Rihl M.F., Pellegrini J.A.S., Boniatti M.M. VExUS Score in the Management of Patients With Acute Kidney Injury in the Intensive Care Unit: AKIVEXStudy. J. Ultrasound Med. 2023; 42 (11): 2547–2556. https://doi.org/10.1002/jum.16288

7. Beaubien-Souligny W., Rola P., Haycock K. et al. Quantifying systemic congestion with Point-Of-Care ultrasound: development of the venous excess ultrasound grading system. Ultrasound J. 2020; 12 (1): 16. https://doi.org/10.1186/s13089-020-00163-w

8. Natraj R., Bhaskaran A.K., Rola P. et al. Venous Congestion Assessed by Venous Excess Ultrasound (VExUS) and Acute Kidney Injury in Children with Right Ventricular Dysfunction. Indian J. Crit. Care Med. 2024; 28 (5): 447–452. https://doi.org/10.5005/jp-journals-10071-24705

9. Andrei S., Bahr P.A., Nguyen M. et al. Prevalence of systemic venous congestion assessed by Venous Excess Ultrasound Grading System (VExUS) and association with acute kidney injury in a general ICU cohort: a prospective multicentric study. Crit. Care. 2023; 27 (1): 224. https://doi.org/10.1186/s13054-023-04524-4

10. Kellum J.A., Lameire N., Aspelin P. et al. Kidney disease: Improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury. Kidney Int. Supplements. 2012; 2 (1): 1–138. https://doi.org/10.1038/kisup.2012.1

11. Song J., Chen G., Lai D. et al. Association between the Venous Excess Ultrasound (VExUS) score and acute kidney injury in critically ill patients with sepsis: a multicenter prospective observational study. Ann. Intens. Care. 2025; 15 (1): 105. https://doi.org/10.1186/s13613-025-01529-w

12. Cao W., Wang R., Wang L., Luo H. Predictive Value of Bedside Ultrasound Evaluation of Venous Excess Ultrasound Grading System for Acute Kidney Injury in Children Undergoing Cardiac Surgery. Ann. Ital. Chir. 2025; 96 (5): 673–680. https://doi.org/10.62713/aic.3966

13. Rola P., Haycock K., Spiegel R. et al. VExUS: common misconceptions, clinical use and future directions. Ultrasound J. 2024; 16 (1): 49. https://doi.org/10.1186/s13089-024-00395-0


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For citations:


Klimentsova N.S., Kamalov Yu.R., Platova E.N., Kryzhanovskaya E.Yu. The capabilities of the VExUS ultrasound scale in predicting acute kidney injury in patients after cardiac surgery. Ultrasound & Functional Diagnostics. (In Russ.) https://doi.org/10.24835/1607-0771-435

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ISSN 1607-0771 (Print)
ISSN 2408-9494 (Online)