usfdУльтразвуковая и функциональная диагностикаUltrasound & Functional Diagnostics1607-07712408-9494RDS-Media Ltd.usfd-254Research ArticleУльтразвуковая диагностика в педиатрииPediatric UltrasoundУльтразвуковое исследование с контрастным усилением у детей - возможности применения в онкологической практикеContrast-Enhanced Ultrasound (CEUS) in Pediatric Oncology (Literature Review)ФеоктистоваЕлена ВладимировнаFeoktistovaE. V.9433572@mail.ruБеляковаЛ. А.BelyakovaL. A.noemail@neicon.ruВарфоломееваС. Р.VarfolomeevaS. R.noemail@neicon.ruФГБУ “Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии имени Дмитрия Рогачева” Министерства здравоохранения Российской ФедерацииDmitry Rogachev Federal Research Center of Pediatric Hematology, Oncology and Immunology201630032024052232Copyright © Феоктистова Е.В., Белякова Л.А., Варфоломеева С.Р., 20242024Феоктистова Е.В., Белякова Л.А., Варфоломеева С.Р.Feoktistova E.V., Belyakova L.A., Varfolomeeva S.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://usfd.rdsmedia.ru/jour/article/view/254

Приведен обзор литературы о применении ультразвукового исследования с контрастным усилением в педиатрии, в том числе в детской онкологии, который показывает все преимущества данного метода обследования. Изложены общепризнанные на сегодняшний день показания и противопоказания к ультразвуковому исследованию с контрастным усилением. Представлены основные ультразвуковые контрастные препараты и их официально разрешенные области применения. Проанализированы данные клинических исследований, указывающие на безопасность применения ультразвуковых контрастных препаратов в детском возрасте. Приведены результаты применения ультразвукового исследования с контрастным усилением для дифференциальной диагностики очаговых поражений печени и динамической оценки кровоснабжения опухоли при проведении таргетной терапии, направленной на подавление ангиогенеза.

Literature review shows the advantages of contrast enhanced ultrasound application in pediatrics, including pediatric oncology. It outlines the current indications and contraindications to contrast enhanced ultrasound. Main ultrasound contrast agents and their officially approved applications are described. The clinical trials data indicating the ultrasound contrast agents application safety in children are presented. The results of contrast enhanced ultrasound application for focal liver lesions differential diagnosis and antiangiogenic treatment response assessment are shown.

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The authors declare that there are no conflicts of interest present.