<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">usfd</journal-id><journal-title-group><journal-title xml:lang="ru">Ультразвуковая и функциональная диагностика</journal-title><trans-title-group xml:lang="en"><trans-title>Ultrasound &amp; Functional Diagnostics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1607-0771</issn><issn pub-type="epub">2408-9494</issn><publisher><publisher-name>RDS-Media Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24835/1607-0771-2023-2-62-79</article-id><article-id custom-type="elpub" pub-id-type="custom">usfd-12</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Другие вопросы ультразвуковой диагностики</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Other trends in ultrasound diagnostics</subject></subj-group></article-categories><title-group><article-title>Ультразвуковое исследование опорно-двигательного аппарата при подагре</article-title><trans-title-group xml:lang="en"><trans-title>Musculoskeletal ultrasound in gout.</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8760-4880</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Полухина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Polukhina</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Полухина Елена Владимировна – доктор мед. наук, доцент, профессор кафедры лучевой и функциональной диагностики</p><p>680009 Хабаровск, ул. Краснодарская, д. 9</p></bio><bio xml:lang="en"><p>Elena V. Polukhina – Doct. of Sci. (Med.), Associate Professor, Professor of Department of Rаdiology and Functional Diagnostics</p><p>9, Krasnodarskaya str., Khabarovsk 680009</p></bio><email xlink:type="simple">polukhina@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>КГБОУ ДПО “Институт повышения квалификации специалистов здравоохранения” Министерства здравоохранения Хабаровского края</institution></aff><aff xml:lang="en"><institution>Postgraduate Institute for Public Health Workers Ministry of Health of the Khabarovsk Region</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>22</day><month>12</month><year>2023</year></pub-date><volume>0</volume><issue>2</issue><fpage>62</fpage><lpage>79</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Полухина Е.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Полухина Е.В.</copyright-holder><copyright-holder xml:lang="en">Polukhina E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://usfd.rdsmedia.ru/jour/article/view/12">https://usfd.rdsmedia.ru/jour/article/view/12</self-uri><abstract><p>Статья представляет собой иллюстрированный обзор литературы, посвященный ультразвуковому исследованию опорно-двигательного аппарата при подагре, являющейся наиболее распространенной причиной воспалительных артропатий у взрослых. На настоящий момент среди методов визуализации ультразвуковое исследование представляет наилучшие возможности в диагностике и мониторировании подагры, позволяя выявить депозиты моноурата натрия в различных структурах суставов, определить наличие и выраженность синовиального воспаления, в том числе для оценки динамики в ответ на уратснижающюю терапию. С позиций последних клинических рекомендаций даны представления об основных эхографических признаках подагры (признак двойного контура, тофусы, агрегаты и эрозии), позволяющих правильно интерпретировать выявленные изменения для своевременной диагностики подагрической артропатии, дифференциальной диагностики и оценки на фоне лечебных мероприятий.</p></abstract><trans-abstract xml:lang="en"><p>The article presents a pictorial literature review on musculoskeletal ultrasound in gout, which is the most common cause of inflammatory arthropathy in adults. Nowadays, among imaging modalities, ultrasound provides the best capabilities for gout diagnosing and monitoring by revealing of monosodium urate deposits in various joint structures, assessing the presence and severity of synovial inflammation, including for dynamical evaluation on urate-lowering therapy. The main ultrasound features of gout (double contour sign, tophi, aggregates and erosions) are described according to the current clinical guidelines. Knowing of these features provides the correct interpretation of ultrasound findings for timely diagnosis and differential diagnosis of gouty arthropathy, and dynamical assessment on therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ультразвуковое исследование</kwd><kwd>подагра</kwd><kwd>гиперурикемия</kwd><kwd>признак двойного контура</kwd><kwd>тофус</kwd><kwd>агрегаты</kwd><kwd>эрозии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ultrasound</kwd><kwd>gout</kwd><kwd>hyperuricemia</kwd><kwd>double contour sign</kwd><kwd>tophus</kwd><kwd>aggregates</kwd><kwd>erosions</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации «Подагра». 2018 г. https://apicr.minzdrav.gov.ru/api.ashx?op=GetClinrecPdf&amp;id=251_1 (дата обращения 10.11.2023)</mixed-citation><mixed-citation xml:lang="en">Clinical guidelines “Gout”, 2018. Available at: https://apicr.minzdrav.gov.ru/api.ashx?op=GetClinrecPdf&amp;id=251_1 (Accessed 10.11.2023) (In Russian</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Richette P., Doherty M., Pascual E., Barskova V., Becce F., Castaneda J., Coyfish M., Guillo S., Jansen T., Janssens H., Lioté F., Mallen C.D., Nuki G., Perez-Ruiz F., Pimentao J., Punzi L., Pywell A., So A.K., Tausche A.K., Uhlig T., Zavada J., Zhang W., Tubach F., Bardin T. 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Ann. Rheum. Dis. 2020; 79(1):31-38. doi: 10.1136/annrheumdis-2019-215315.</mixed-citation><mixed-citation xml:lang="en">Richette P., Doherty M., Pascual E., Barskova V., Becce F., Castaneda J., Coyfish M., Guillo S., Jansen T., Janssens H., Lioté F., Mallen C.D., Nuki G., Perez-Ruiz F., Pimentao J., Punzi L., Pywell A., So A.K., Tausche A.K., Uhlig T., Zavada J., Zhang W., Tubach F., Bardin T. 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout. Ann. Rheum. Dis. 2020; 79 (1): 31–38. http://doi.org/10.1136/annrheumdis-2019215315</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">FitzGerald J.D., Dalbeth N., Mikuls T., Brignardello-Petersen R., Guyatt G., Abeles A.M., Gelber A.C., Harrold L.R., Khanna D., King C., Levy G., Libbey C., Mount D., Pillinger M.H., Rosenthal A., Singh J.A., Sims J.E., Smith B.J., Wenger N.S., Bae S.S., Danve A.., Khanna P.P., Kim S.C., Lenert A., Poon S., Qasim A.., Sehra S.T., Sharma T.S.K., Toprover M., Turgunbaev M., Zeng L., Zhang M.A., Turner A.S., Neogi T. 2020 American College of Rheumatology Guideline for the Management of Gout. Arthritis Rheumatol. 2020; 72(6):879-895. doi: 10.1002/art.41247.</mixed-citation><mixed-citation xml:lang="en">FitzGerald J.D., Dalbeth N., Mikuls T., Brignardello-Petersen R., Guyatt G., Abeles A.M., Gelber A.C., Harrold L.R., Khanna D., King C., Levy G., Libbey C., Mount D., Pillinger M.H., Rosenthal A., Singh J.A., Sims J.E., Smith B.J., Wenger N.S., Bae S.S., Danve A., Khanna P.P., Kim S.C., Lenert A., Poon S., Qasim A., Sehra S.T., Sharma T.S.K., Toprover M., Turgunbaev M., Zeng L., Zhang M.A., Turner A.S., Neogi T. 2020 American College of Rheumatology Guideline for the Management of Gout. Art. Rheumatol. 2020; 72 (6): 879–895. http://doi.org/10.1002/art.41247</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bardin T., Richette P. Definition of hyperuricemia and gouty conditions. Curr. Opin. Rheumatol. 2014; 26(2):186-191. doi: 10.1097/BOR.0000000000000028.</mixed-citation><mixed-citation xml:lang="en">Bardin T., Richette P. Definition of hyperuricemia and gouty conditions. Curr. Opin. Rheumatol. 2014; 26 (2): 186–191. http://doi.org/10.1097/BOR.0000000000000028.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Weaver J.S., Vina E.R, Munk P.L., Klauser A.S., Elifritz J.M, Taljanovic M.S. Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging. J. Clin. Med. 2021; 29;11(1):166. doi: 10.3390/jcm11010166.</mixed-citation><mixed-citation xml:lang="en">Weaver J.S., Vina E.R, Munk P.L., Klauser A.S., Elifritz J.M, Taljanovic M.S. Gouty Arthropathy: Review of Clinical Manifestations and Treatment, with Emphasis on Imaging. J. Clin. Med. 2021; 29; 11 (1): 166. http://doi.org/10.3390/jcm11010166</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Stewart S., Su I., Gamble G.D., Dalbeth N. Diagnostic value of different imaging features for patients with suspected gout: A network meta-analysis. Semin Arthritis Rheum. 2021; 51(6):1251-1257. doi: 10.1016/j.semarthrit.2021.10.005.</mixed-citation><mixed-citation xml:lang="en">Stewart S., Su I., Gamble G.D., Dalbeth N. Diagnostic value of different imaging features for patients with suspected gout: A network metaanalysis. Semin. Art. Rheum. 2021; 51 (6): 1251– 1257. http://doi.org/10.1016/j.semarthrit. 2021.10.005</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Lee Y.H., Song G.G. Diagnostic accuracy of ultrasound in patients with gout: A meta-analysis. Semin Arthritis Rheum. 2018; 47(5):703-709. doi: 10.1016/j.semarthrit.2017.09.012.</mixed-citation><mixed-citation xml:lang="en">Lee Y.H., Song G.G. Diagnostic accuracy of ultrasound in patients with gout: A meta-analysis. Semin. Art. Rheum. 2018; 47 (5): 703–709. http://doi.org/10.1016/j.semarthrit.2017.09.012</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Pastor C.M., Perez E.A., Casares E.G. Usefulness of ultrasound in the diagnosis of crystal deposition diseases. Eur. J. Rheumatol. 2022. doi: 10.5152/eurjrheum.2022.20129.</mixed-citation><mixed-citation xml:lang="en">Pastor C.M., Perez E.A., Casares E.G. Usefulness of ultrasound in the diagnosis of crystal deposition diseases. Eur. J. Rheumatol. 2022. http://doi.org/10.5152/eurjrheum.2022.20129.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Gutierrez M., Schmidt W.A., Thiele R.G., Keen H.I., Kaeley G.S., Naredo E., Iagnocco A., Bruyn G.A., Balint P.V., Filippucci E., Mandl P., Kane D., Pineda C., Delle Sedie A., Hammer H.B., Christensen R., D'Agostino M.A., Terslev L. OMERACT Ultrasound Gout Task Force group. International Consensus for ultrasound lesions in gout: results of Delphi process and web-reliability exercise. Rheumatology (Oxford). 2015; 54(10):1797-1805. doi: 10.1093/rheumatology/kev112.</mixed-citation><mixed-citation xml:lang="en">Gutierrez M., Schmidt W.A., Thiele R.G., Keen H.I., Kaeley G.S., Naredo E., Iagnocco A., Bruyn G.A., Balint P.V., Filippucci E., Mandl P., Kane D., Pineda C., Delle Sedie A., Hammer H.B., Christensen R., D'Agostino M.A., Terslev L. OMERACT Ultrasound Gout Task Force group. International Consensus for ultrasound lesions in gout: results of Delphi process and web-reliability exercise. Rheumatology (Oxford). 2015; 54 (10): 1797–1805. http://doi.org/10.1093/rheumatology/kev112.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Towiwat P., Chhana A., Dalbeth N. The anatomical pathology of gout: a systematic literature review. BMC Musculoskelet Disord. 2019; 20(1):140. doi: 10.1186/s12891-019-2519-y.</mixed-citation><mixed-citation xml:lang="en">Towiwat P., Chhana A., Dalbeth N. The anatomical pathology of gout: a systematic literature review. BMC Musculoskelet Disord. 2019; 20 (1): 140. http://doi.org/10.1186/s12891-019-2519-y</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang W., Jin Z., Xiang W., Wu M., Wang S., Zhang H., Zhang P. Ultrasonographic Features of Lower-Limb Joints in Gout: Which Joints and Clinical Characteristics Would Provide More Information for Diagnosis? J. Clin. Rheumatol. 2020; 26(1):14-18. doi: 10.1097/RHU.0000000000000898.</mixed-citation><mixed-citation xml:lang="en">Zhang W., Jin Z., Xiang W., Wu M., Wang S., Zhang H., Zhang P. Ultrasonographic Features of Lower-Limb Joints in Gout: Which Joints and Clinical Characteristics Would Provide More Information for Diagnosis? J. Clin. Rheumatol. 2020; 26 (1): 14–18. http://doi.org/10.1097/RHU.0000000000000898</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Filippucci E., Reginato A.M., Thiele R.G. Imaging of crystalline arthropathy in 2020. Best Pract. Res. Clin. Rheumatol. 2020; 34(6):101595. doi: 10.1016/j.berh.2020.101595.</mixed-citation><mixed-citation xml:lang="en">Filippucci E., Reginato A.M., Thiele R.G. Imaging of crystalline arthropathy in 2020. Best Pract. Res. Clin. Rheumatol. 2020; 34 (6): 101595. http://doi.org/10.1016/j.berh.2020.101595</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ogdie A., Taylor W.J,. Neogi T., Fransen J., Jansen T.L., Schumacher H.R., Louthrenoo W., Vazquez-Mellado J., Eliseev M., McCarthy G., Stamp L.K., Perez-Ruiz F., Sivera F., Ea H..K, Gerritsen M., Cagnotto G, Cavagna L., Lin C., Chou Y.Y, Tausche A.K., Lima Gomes Ochtrop M., Janssen M., Chen J.H., Slot O., Lazovskis .J, White D., Cimmino M.A., Uhlig T., Dalbeth N. Performance of Ultrasound in the Diagnosis of Gout in a Multicenter Study: Comparison With Monosodium Urate Monohydrate Crystal Analysis as the Gold Standard. Arthritis Rheumatol. 2017; 69(2):429-438. doi: 10.1002/art.39959.</mixed-citation><mixed-citation xml:lang="en">Ogdie A., Taylor W.J,. Neogi T., Fransen J., Jansen T.L., Schumacher H.R., Louthrenoo W., Vazquez-Mellado J., Eliseev M., McCarthy G., Stamp L.K., Perez-Ruiz F., Sivera F., Ea H..K, Gerritsen M., Cagnotto G, Cavagna L., Lin C., Chou Y.Y, Tausche A.K., Lima Gomes Ochtrop M., Janssen M., Chen J.H., Slot O., Lazovskis .J, White D., Cimmino M.A., Uhlig T., Dalbeth N. Performance of Ultrasound in the Diagnosis of Gout in a Multicenter Study: Comparison With Monosodium Urate Monohydrate Crystal Analysis as the Gold Standard. Art. Rheumatol. 2017; 69 (2): 429–438. http://doi.org/10.1002/art.39959</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Neogi T., Jansen T.L., Dalbeth N., Fransen J., Schumacher H.R., Berendsen D., Brown M., Choi H., Edwards N.L., Janssens H.J., Lioté F., Naden R.P., Nuki G., Ogdie A., Perez-Ruiz F., Saag K., Singh J.A., Sundy J.S., Tausche A.K., Vaquez-Mellado J., Yarows S.A., Taylor W.J. 2015 Gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann Rheum Dis. 2015; 74(10):1789-1798. doi: 10.1136/annrheumdis-2015-208237.</mixed-citation><mixed-citation xml:lang="en">Neogi T., Jansen T.L., Dalbeth N., Fransen J., Schumacher H.R., Berendsen D., Brown M., Choi H., Edwards N.L., Janssens H.J., Lioté F., Naden R.P., Nuki G., Ogdie A., Perez-Ruiz F., Saag K., Singh J.A., Sundy J.S., Tausche A.K., Vaquez-Mellado J., Yarows S.A., Taylor W.J. 2015 Gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Ann. Rheum. Dis. 2015; 74 (10): 1789–1798. http://doi.org/10.1136/annrheumdis-2015-208237</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Filippou G., Scirè C.A., Damjanov N., Adinolfi A., Carrara G., Picerno V., Toscano C., Bruyn G.A., D'Agostino M.A., Delle Sedie A., Filippucci E., Gutierrez M., Micu M., Möller I., Naredo E., Pineda C., Porta F., Schmidt W.A., Terslev L., Vlad V., Zufferey P., Iagnocco A. Definition and Reliability Assessment of Elementary Ultrasonographic Findings in Calcium Pyrophosphate Deposition Disease: A Study by the OMERACT Calcium Pyrophosphate Deposition Disease Ultrasound Subtask Force. J. Rheumatol. 2017; 44(11):1744-1749. doi: 10.3899/jrheum.161057.</mixed-citation><mixed-citation xml:lang="en">Filippou G., Scirè C.A., Damjanov N., Adinolfi A., Carrara G., Picerno V., Toscano C., Bruyn G.A., D'Agostino M.A., Delle Sedie A., Filippucci E., Gutierrez M., Micu M., Möller I., Naredo E., Pineda C., Porta F., Schmidt W.A., Terslev L., Vlad V., Zufferey P., Iagnocco A. Definition and Reliability Assessment of Elementary Ultrasonographic Findings in Calcium Pyro phosphate Deposition Disease: A Study by the OMERACT Calcium Pyrophosphate Deposition Disease Ultrasound Subtask Force. J. Rheumatol. 2017; 44 (11): 1744–1749. http://doi.org/10.3899/jrheum.161057</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Filippou G., Miguel-Pérez M., Coronel L., Sirotti S., Pacini G., Scanu A., Bong D., Möller I. EULAR Study Group on Anatomy for the Image. The ultrasonographic pseudo-double contour sign in calcium pyrophosphate deposition disease: an anatomic explanation and how to distinguish it from gout. Arthritis Rheumatol. 2023; 75(4):639-640. doi: 10.1002/art.42397.</mixed-citation><mixed-citation xml:lang="en">Filippou G., Miguel-Pérez M., Coronel L., Sirotti S., Pacini G., Scanu A., Bong D., Möller I. EULAR Study Group on Anatomy for the Image. The ultrasonographic pseudo-double contour sign in calcium pyrophosphate deposition disease: an anatomic explanation and how to distinguish it from gout. Art. Rheumatol. 2023; 75 (4): 639–640. http://doi.org/10.1002/art.42397</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Cipolletta E., Abhishek A., Di Matteo A., Grassi W., Filippucci E. Dynamic assessment of the double contour sign by ultrasonography helps to distinguish between gout and calcium pyrophosphate deposition disease. RMD Open. Published online March 16, 2023. doi:10.1136/rmdopen-2022-002940</mixed-citation><mixed-citation xml:lang="en">Cipolletta E., Abhishek A., Di Matteo A., Grassi W., Filippucci E. Dynamic assessment of the double contour sign by ultrasonography helps to distinguish between gout and calcium pyrophosphate deposition disease. RMD Open. Published online March 16, 2023. http://doi.org/10.1136/rmdopen-2022-002940</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Dalbeth N., Pool B., Gamble G.D., Smith T., Callon K.E., McQueen F.M., Cornish J. Cellular characterization of the gouty tophus: a quantitative analysis. Arthritis Rheum. 2010; 62(5):1549-1556. doi: 10.1002/art.27356.</mixed-citation><mixed-citation xml:lang="en">Dalbeth N., Pool B., Gamble G.D., Smith T., Callon K.E., McQueen F.M., Cornish J. Cellular characterization of the gouty tophus: a quantitative analysis. Art. Rheum. 2010; 62 (5): 1549–1556. http://doi.org/10.1002/art.27356</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Ventura-Ríos L., Sánchez-Bringas G., Pineda C., Hernández-Díaz C., Reginato A., Alva M., Audisio M., Bertoli A., Cazenave T., Gutiérrez M., Mora C., Py G., Sedano O., Solano C., de Miguel E. Tendon involvement in patients with gout: an ultrasound study of prevalence. Clin. Rheumatol. 2016; 35(8):2039-2044. doi: 10.1007/s10067-016-3309-7.</mixed-citation><mixed-citation xml:lang="en">Ventura-Ríos L., Sánchez-Bringas G., Pineda C., Hernández-Díaz C., Reginato A., Alva M., Audisio M., Bertoli A., Cazenave T., Gutiérrez M., Mora C., Py G., Sedano O., Solano C., de Miguel E. Tendon involvement in patients with gout: an ultrasound study of prevalence. Clin. Rheumatol. 2016; 35 (8): 2039–2044. http://doi.org/10.1007/s10067-016-3309-7</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Q., Guo L.H., Li X.L, Zhao C.K., Li M.X., Wang L., Liu X.Y., Xu H.X. Differentiating the acute phase of gout from the intercritical phase with ultrasound and quantitative shear wave elastography. Eur. Radiol. 2018; 28(12):5316-5327. doi: 10.1007/s00330-018-5529-5.</mixed-citation><mixed-citation xml:lang="en">Wang Q., Guo L.H., Li X.L, Zhao C.K., Li M.X., Wang L., Liu X.Y., Xu H.X. Differentiating the acute phase of gout from the intercritical phase with ultrasound and quantitative shear wave elastography. Eur. Radiol. 2018; 28 (12): 5316–5327. http://doi.org/10.1007/s00330-018-5529-5</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Tang Y., Yan F., Yang Y., Xiang X., Wang L., Zhang L., Qiu L. Value of Shear Wave Elastography in the Diagnosis of Gouty and Non-Gouty Arthritis. Ultrasound Med Biol. 2017; 43(5): 884-892. doi: 10.1016/j.ultrasmedbio.2016.12.012.</mixed-citation><mixed-citation xml:lang="en">Tang Y., Yan F., Yang Y., Xiang X., Wang L., Zhang L., Qiu L. Value of Shear Wave Elastography in the Diagnosis of Gouty and Non-Gouty Arthritis. Ultrasound Med. Biol. 2017; 43 (5): 884–892. http://doi.org/10.1016/j.ultrasmedbio.2016. 12.012</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Taljanovic M.S., Gimber L.H.., Becker G.W., Latt L.D., Klauser A.S., Melville D.M., Gao L., Witte R.S. Shear-Wave Elastography: Basic Physics and Musculoskeletal Applications. Radiographics. 2017; 37(3):855-870. doi: 10.1148/rg.2017160116.</mixed-citation><mixed-citation xml:lang="en">Taljanovic M.S., Gimber L.H.., Becker G.W., Latt L.D., Klauser A.S., Melville D.M., Gao L., Witte R.S. Shear-Wave Elastography: Basic Physics and Musculoskeletal Applications. Radiographics. 2017; 37 (3): 855–870. http://doi.org/10.1148/rg.2017160116</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Christiansen S.N., Filippou G., Scirè C.A., Balint P.V., Bruyn G.A., Dalbeth N., Dejaco C., Sedie A.D., Filippucci E., Hammer H.B., Iagnocco A, Keen H.I., Kissin E.Y., Koski J., Mandl P., Martin J., Miguel E., Möller I., Naredo E., Pineda C., Schmidt W.A., Stewart S., Antonietta D'Agostino M., Terslev L.; on the behalf of the OMERACT Ultrasound working group. Consensus-based semi-quantitative ultrasound scoring system for gout lesions: Results of an OMERACT Delphi process and web-reliability exercise. Semin. Arthritis Rheum. 2021; 51(3):644-649. doi: 10.1016/j.semarthrit.2020.11.011.</mixed-citation><mixed-citation xml:lang="en">Christiansen S.N., Filippou G., Scirè C.A., Balint P.V., Bruyn G.A., Dalbeth N., Dejaco C., Sedie A.D., Filippucci E., Hammer H.B., Iagnocco A, Keen H.I., Kissin E.Y., Koski J., Mandl P., Martin J., Miguel E., Möller I., Naredo E., Pineda C., Schmidt W.A., Stewart S., Antonietta D'Agostino M., Terslev L.; on the behalf of the OMERACT Ultrasound working group. Consensusbased semi-quantitative ultrasound scoring system for gout lesions: Results of an OMERACT Delphi process and web-reliability exercise. Semin. Art. Rheum. 2021; 51 (3): 644–649. http://doi.org/10.1016/j.semarthrit.2020.11.011</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Dalbeth N., Clark B., Gregory K., Gamble G., Sheehan T., Doyle A., McQueen F.M. Mechanisms of bone erosion in gout: a quantitative analysis using plain radiography and computed tomography. Ann Rheum Dis. 2009; 68(8):1290-1295. doi: 10.1136/ard.2008.094201.</mixed-citation><mixed-citation xml:lang="en">Dalbeth N., Clark B., Gregory K., Gamble G., Sheehan T., Doyle A., McQueen F.M. Mechanisms of bone erosion in gout: a quantitative analysis using plain radiography and computed tomography. Ann. Rheum. Dis. 2009; 68 (8): 1290–1295. http://doi.org/10.1136/ard.2008.094201</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Wu M., Liu F.J., Chen J., Chen L., Wei C., Hu Z.M., Han Y., Lu J.X., Jiang L.X., Chen H.B. Prevalence and Factors Associated With Bone Erosion in Patients With Gout. Arthritis Care Res (Hoboken). 2019; 71(12):1653-1659. doi: 10.1002/acr.23816.</mixed-citation><mixed-citation xml:lang="en">Wu M., Liu F.J., Chen J., Chen L., Wei C., Hu Z.M., Han Y., Lu J.X., Jiang L.X., Chen H.B. Prevalence and Factors Associated With Bone Erosion in Patients With Gout. Art. Care Res. (Hoboken). 2019; 71 (12): 1653–1659. http://doi.org/10.1002/acr.23816</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang Q., Gao F., Sun W., Ma J., Cheng L., Li Z. The diagnostic performance of musculoskeletal ultrasound in gout: A systematic review and meta-analysis. PLoS One. 2018; 13(7):e0199672. doi: 10.1371/journal.pone.0199672.</mixed-citation><mixed-citation xml:lang="en">Zhang Q., Gao F., Sun W., Ma J., Cheng L., Li Z. The diagnostic performance of musculoskeletal ultrasound in gout: A systematic review and metaanalysis. PLoS One. 2018; 13 (7): e0199672. http://doi.org/10.1371/journal.pone.0199672</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Bhadu D., Das S.K., Wakhlu A., Dhakad U., Sharma M. Ultrasonographic detection of double contour sign and hyperechoic aggregates for diagnosis of gout: two sites examination is as good as six sites examination. Int. J. Rheum. Dis. 2018; 21(2):523-531. doi: 10.1111/1756-185X.13235.</mixed-citation><mixed-citation xml:lang="en">Bhadu D., Das S.K., Wakhlu A., Dhakad U., Sharma M. Ultrasonographic detection of double contour sign and hyperechoic aggregates for diagnosis of gout: two sites examination is as good as six sites examination. Int. J. Rheum. Dis. 2018; 21 (2): 523–531. http://doi.org/10.1111/1756-185X.13235</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Christiansen S.N., Østergaard M., Slot O., Keen H., Bruyn G.A.W., D'Agostino M.A., Terslev L. Assessing the sensitivity to change of the OMERACT ultrasound structural gout lesions during urate-lowering therapy. RMD Open. 2020; 6(1):e001144. doi: 10.1136/rmdopen-2019-001144.</mixed-citation><mixed-citation xml:lang="en">Christiansen S.N., Østergaard M., Slot O., Keen H., Bruyn G.A.W., D'Agostino M.A., Terslev L. Assessing the sensitivity to change of the OMERACT ultrasound structural gout lesions during uratelowering therapy. RMD Open. 2020; 6 (1): e001144. http://doi.org/10.1136/rmdopen-2019-001144</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Hammer H.B., Karoliussen L., Terslev L., Haavardsholm E.A., Kvien T.K., Uhlig T. Ultrasound shows rapid reduction of crystal depositions during a treat-to-target approach in gout patients: 12-month results from the NOR-Gout study. Ann Rheum Dis. 2020; 79(11):1500-1505. doi: 10.1136/annrheumdis-2020-217392.</mixed-citation><mixed-citation xml:lang="en">Hammer H.B., Karoliussen L., Terslev L., Haavardsholm E.A., Kvien T.K., Uhlig T. Ultrasound shows rapid reduction of crystal depositions during a treat-to-target approach in gout patients: 12-month results from the NOR-Gout study. Ann. Rheum. Dis. 2020; 79 (11): 1500–1505. doi: 10.1136/annrheumdis-2020-217392.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Yuan H., Fan Y., Mou X., Qing Y., Yan X., Tang X., Yue W., Gu P., Yang Q., He Y. Musculoskeletal Ultrasound in Monitoring the Efficacy of Gout: A Prospective Study Based on Tophus and Double Contour Sign. Balkan Med. J. 2023; 40(2):104-110. doi: 10.4274/balkanmedj.galenos.2022.2022-7-39.</mixed-citation><mixed-citation xml:lang="en">Yuan H., Fan Y., Mou X., Qing Y., Yan X., Tang X., Yue W., Gu P., Yang Q., He Y. Musculoskeletal Ultrasound in Monitoring the Efficacy of Gout: A Prospective Study Based on Tophus and Double Contour Sign. Balkan Med. J. 2023; 40 (2): 104–110. http://doi.org/10.4274/balkanmedj.galenos.2022.2022-7-39</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
